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You are here:Home » Antibodies » Abs to Ion Channel » Anti -CACNA1C (Voltage-dependent L-type Calcium Channel Subunit alpha-1C, Calcium Channel, L Type, alpha-1 Polypeptide, Isoform 1, Cardiac Muscle, Voltage-gated Calcium Channel Subunit alpha Cav1.2, CACH2, CACN2, CACNL1A1, CCHL1A1)

Anti -CACNA1C (Voltage-dependent L-type Calcium Channel Subunit alpha-1C, Calcium Channel,
L Type, alpha-1 Polypeptide, Isoform 1, Cardiac Muscle, Voltage-gated Calcium Channel
Subunit alpha Cav1.2, CACH2, CACN2, CACNL1A1, CCHL1A1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Many alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Catalog #124204
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
AA SequenceAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No4D10
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPartial recombinant corresponding to aa2039-2138 from human CACNA1C (NP_000710) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human CACNA1C.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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