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You are here:Home » Antibodies » Abs to Neuroscience » Anti -Calcipressin 1 (DSCR1, Regulator Of Calcineurin 1, DSCR1, Down Syndrome Critical Region Protein 1, Myocyte-enriched Calcineurin-interacting Protein 1, MCIP1, Adapt78, RCAN1, DSC1, CSP1)

Anti -Calcipressin 1 (DSCR1, Regulator Of Calcineurin 1, DSCR1, Down Syndrome Critical
Region Protein 1, Myocyte-enriched Calcineurin-interacting Protein 1, MCIP1, Adapt78,
RCAN1, DSC1, CSP1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B
DSCR1 interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. The gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of DSCR1 may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
Catalog #124246
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
AA SequenceMEEVDLQDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPN
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No1G7
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in ascites fluid.
PurityAscites
ImmunogenPartial recombinant corresponding to aa1-100 from human DSCR1 (AAH02864) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human DSCR1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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