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You are here:Home » Antibodies » Abs to Centromeres » Anti -CENPJ (Centromere Protein J, CENP-J, BM032, Centrosomal P4.1-associated Protein, CPAP, LAG-3-associated Protein, LAP, LYST-interacting Protein 1, LIP1, MCPH6, MGC131581, MGC131582, MGC142222, MGC142224)

Anti -CENPJ (Centromere Protein J, CENP-J, BM032, Centrosomal P4.1-associated Protein,
CPAP, LAG-3-associated Protein, LAP, LYST-interacting Protein 1, LIP1, MCPH6, MGC131581,
MGC131582, MGC142222, MGC142224)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.
Catalog #124853
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 1.5ug/ml
Optimal dilutions to be determined by the researcher.
AA SequenceKYTTAARTFPDKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAIESSLEVEKKDKLANTSVRFQNSQISSGTQ
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No5D5
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPartial recombinant corresponding to aa979-1089 from human CENPJ (NP_060921) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human CENPJ.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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