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You are here:Home » Antibodies » Abs to Neuroscience » Anti -Collapsin Response Mediator Protein 4 (CRMP-4, CRMP4, Dihydropyrimidinase-like 3, DPYSL3, Dihydropyrimidinase-related Protein 3, DRP-3, DRP3, LCRMP, TUC4, Unc-33-like Phosphoprotein, ULIP, Ulip-1)

Anti -Collapsin Response Mediator Protein 4 (CRMP-4, CRMP4, Dihydropyrimidinase-like 3,
DPYSL3, Dihydropyrimidinase-related Protein 3, DRP-3, DRP3, LCRMP, TUC4, Unc-33-like
Phosphoprotein, ULIP, Ulip-1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
DRP-3 belongs to the hydantoinase/dihydropyrimidase subfamily. It is required for signalling by class 3 semaphorins and remodelling of the cytoskeleton. It also plays a role in axon guidance, neuronal growth cone collapse and cell migration. It exists as a homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL4 or DPYSL5. The unprocessed precursor is 570 amino acids long and has an estimated molecular weight of 61.9kD. It is mainly expressed in heart and skeletal muscle, but is also strongly expressed in fetal brain and spinal cord. It localizes to the cytoplasm and growth cone. This protein interacts with synaptic vesicle protein 2 and SH3A domain of intersectin.
Catalog #125200
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 3ug/ml
Optimal dilutions to be determined by the researcher.
AA SequenceGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSARGSPTRPNPPVRNLHQSGFSLSGTQVDEGVRSASKR
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No1B8
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPartial recombinant corresponding to aa457-555 from human DPYSL3 (NP_001378) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human DPYSL3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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