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You are here:Home » Antibodies » Abs to Enzymes, Polymerase » Anti -CRSP8 (P37 TRAP/SMCC/PC2 Subunit, Transcriptional Coactivator CRSP34, CRSP Complex Subunit 8, Cofactor Required For Sp1 Transcriptional Activation Subunit 8, Mediator Complex Subunit 27, Mediator Of RNA Polymerase II Transcription Subunit 27, MED27, CRSP3

Anti -CRSP8 (P37 TRAP/SMCC/PC2 Subunit, Transcriptional Coactivator CRSP34, CRSP Complex
Subunit 8, Cofactor Required For Sp1 Transcriptional Activation Subunit 8, Mediator
Complex Subunit 27, Mediator Of RNA Polymerase II Transcription Subunit 27, MED27, CRSP3

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. CRSP8 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Catalog #125353
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
AA SequenceMADVINVSVNLEAFSQAISAIQALRSSVSRVFDCLKDGMRNKETLEGREKAFIAHFQDNLHSVNRDLNELERLSNLVGKPSENHPLHNSGLLSLDPVQDKTPLYSQLLQAYKWSNKLQYHAGLASGLLNQQSLKRSANQMGVSAKRRPKAQPTTLVLPPQYVDDVISRIDRMFPEMSIHLSRPNGTSAMLLVTLGKVLKVIVVMRSLFIDRTIVKGYNENVYTEDGKLDIWSKSNYQVFQKVTDHATTALLHYQLPQMPDVVVRSFMTWLRSYIKLFQAPCQRCGKFLQDGLPPTWRDFRTLEAFHDTCRQ
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenFull length human MED27, aa1-311 (NP_004260.2).
SpecificityRecognizes human MED27.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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