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You are here:Home » Antibodies » Abs to Catenin » Anti -CTNNA3 (Catenin alpha-3, Alpha T-catenin, Cadherin-associated Protein)

Anti -CTNNA3 (Catenin alpha-3, Alpha T-catenin, Cadherin-associated Protein)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Alpha-catenins stabilize the cell-cell contacts by functioning as a molecular switch that regulates actin dynamics at the site of the adherens junction. Alpha-T Catenin is involved in the formation of stretch-resistant cell-cell adhesion complexes. Alpha-T catenin is expressed predominantly in cardiomyocytes, where it colocalizes with alpha-E catenin at the intercalated discs. Moreover, alpha-T Catenin is also expressed in the brain and inhibits Wnt signaling, so it is implicated in Alzheimer's disease.
Catalog #125451
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
AA SequenceMSAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCPQNPSSRKKGRSKRASVLLASVEEATWNLLDKGEKIAQEATVLKDELTASLEKVRKESEALKVSAERFTDDPCFLPKREAVVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKELENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDTVCEEIQNALNVISNA
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No3F4-1B11
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenFull length recombinant corresponding to aa1-590 from human CTNNA3 (AAH22004) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human CTNNA3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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