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You are here:Home » Antibodies » Abs to Translation Initiation Factors » Anti -EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon-1, Aminoacyl tRNA Synthetase Complex-interacting Multifunctional Protein 3, Elongation Factor p18, Multisynthase Complex Auxiliary Component p18, AIMP3, P18)

Anti -EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon-1, Aminoacyl tRNA
Synthetase Complex-interacting Multifunctional Protein 3, Elongation Factor p18,
Multisynthase Complex Auxiliary Component p18, AIMP3, P18)

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Specifications

Clone Host Grade Applications
Polyclonal Mouse Affinity Purified B IF
The normal progression of cells through the cell cycle is under the control of the cyclin dependent protein kinases Cdk4 and Cdk6, which are subject to inhibition by the mitotic inhibitory protein p16. Isolated members of the p16 family have been designated p15 and p18, respectively. The p16 related protein, p18, interacts strongly with Cdk6 and, to a lesser extent, with Cdk4, but lacks apparent interaction with other Cdks. Recombinant p18 has been shown to inhibit cyclin D-Cdk6 kinase activity. In contrast to p21/p27, which forms ternary complexes with cyclin-Cdks, and only binary complexes of p15, p16 and p18 have been identified in association with Cdk4 and/or Cdk6.
Catalog #126171
ApplicationsSuitable for use in Immunofluorescence and Western Blot. Other applications not tested.
Recommended DilutionImmunofluorescence: 10ug/ml
Optimal dilutions to be determined by the researcher.
AA SequenceMAAAAELSLLEKSLGLSKGNKYSAQGERQIPVLQTNNGPSLTGLTTIAAHLVKQANKEYLLGSTAEEKAIVQQWLEYRVTQVDGHSSKNDIHTLLKDLNSYLEDKVYLTGYNFTLADILLYYGLHRFIVDLTVQEKEKYLNVSRWFCHIQHYPGIRQHLSSVVFIKNRLYTNSH
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenFull length human EEF1E1, aa1-174 (NP_004271.1).
SpecificityRecognizes human EEF1E1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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