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You are here:Home » Antibodies » Abs to Ribosomal Proteins » Anti -EXOSC4 (RRP41, SKI6, Exosome Complex Component RRP41, Exosome Component 4, Ribosomal RNA-processing Protein 41, p12A, FLJ20591, RRP41A, Rrp41p, SKI6, Ski6p, HRrp41p)

Anti -EXOSC4 (RRP41, SKI6, Exosome Complex Component RRP41, Exosome Component 4, Ribosomal
RNA-processing Protein 41, p12A, FLJ20591, RRP41A, Rrp41p, SKI6, Ski6p, HRrp41p)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. Required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity. Plays a role in replication-dependent histone mRNA degradation.
Catalog #126512
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
AA SequenceMAGLELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMG
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No4F10
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPartial recombinant corresponding to aa1-101 from human EXOSC4 (NP_061910) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human EXOSC4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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