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You are here:Home » Antibodies » Abs to Transcription Factors, Homeobox (HOX) » Anti -HOXB8 (Homeobox Protein Hox-B8, Homeobox Protein Hox-2.4, Homeobox Protein Hox-2D, HOX2D)

Anti -HOXB8 (Homeobox Protein Hox-B8, Homeobox Protein Hox-2.4, Homeobox Protein Hox-2D,
HOX2D)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
HOXB8 is a member of the Antp homeobox family. It is a sequence specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior posterior axis during development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive compulsive spectrum disorder trichotillomania.
Catalog #128025
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
AA SequenceGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAA
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No4F8
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPartial recombinant corresponding to aa16-114 from human HOXB8 (NP_076921) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human HOXB8.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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