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You are here:Home » Antibodies » Abs to Obesity Proteins » Anti -MED1 (Mediator of RNA Polymerase II Transcription Subunit 1, Activator-recruited Cofactor 205kD Component, ARC205, Mediator Complex Subunit 1, Peroxisome Proliferator-activated Receptor-binding Protein, PBP, PPAR-binding Protein, Thyroid Hormone Receptor-

Anti -MED1 (Mediator of RNA Polymerase II Transcription Subunit 1, Activator-recruited
Cofactor 205kD Component, ARC205, Mediator Complex Subunit 1, Peroxisome
Proliferator-activated Receptor-binding Protein, PBP, PPAR-binding Protein, Thyroid
Hormone Receptor-

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IF
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Catalog #129537
ApplicationsSuitable for use in Immunofluorescence, ELISA and Western Blot. Other applications not tested.
Recommended DilutionImmunofluorescence: 10ug/ml
Optimal dilutions to be determined by the researcher.
AA SequenceKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLP
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No2A2
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPartial recombinant corresponding to aa1391-1491 from human PPARBP (NP_004765) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human PPARBP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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