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You are here:Home » Antibodies » Abs to RNA Processing » Anti -NUDT3 (Diphosphoinositol Polyphosphate Phosphohydrolase 1, DIPP-1, Diadenosine 5',5'''-P1,P6-hexaphosphate Hydrolase 1, Nucleoside Diphosphate-linked Moiety X Motif 3, Nudix Motif 3, DIPP, DIPP1)

Anti -NUDT3 (Diphosphoinositol Polyphosphate Phosphohydrolase 1, DIPP-1, Diadenosine
5',5'''-P1,P6-hexaphosphate Hydrolase 1, Nucleoside Diphosphate-linked Moiety X Motif 3,
Nudix Motif 3, DIPP, DIPP1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate) and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. InsP6 (inositol hexakisphophate) is not a substrate. Acts as a negative regulator of the ERK1/2 pathway. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.
Catalog #130633
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
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Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No3C5
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenFull length recombinant corresponding to aa1-173 from NUDT3 (AAH07727, ) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human NUDT3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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