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You are here:Home » Antibodies » Abs to Adapter Proteins » Anti -PARD3 (Partitioning Defective 3 Homolog, PAR-3, PARD-3, Atypical PKC Isotype-specific-interacting Protein, ASIP, CTCL Tumor Antigen se2-5, PAR3-alpha, PAR3, PAR3A, Bazooka, FLJ21015, SE2-5L16, SE2-5LT1, SE2-5T2)

Anti -PARD3 (Partitioning Defective 3 Homolog, PAR-3, PARD-3, Atypical PKC
Isotype-specific-interacting Protein, ASIP, CTCL Tumor Antigen se2-5, PAR3-alpha, PAR3,
PAR3A, Bazooka, FLJ21015, SE2-5L16, SE2-5LT1, SE2-5T2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.
Catalog #130874
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
AA SequenceKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPS
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No4G5
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPartial recombinant corresponding to aa181-290 from human PARD3 (AAH11711) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human PARD3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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