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You are here:Home » Antibodies » Antibodies-Enzymes, Ribonuclease » Anti -PARN (Poly(A)-specific Ribonuclease PARN, Deadenylating Nuclease, Deadenylation Nuclease, Polyadenylate-specific Ribonuclease, DAN)

Anti -PARN (Poly(A)-specific Ribonuclease PARN, Deadenylating Nuclease, Deadenylation
Nuclease, Polyadenylate-specific Ribonuclease, DAN)


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Clone Host Grade Applications
Polyclonal Mouse Affinity Purified B IF
Poly(A) ribonuclease (PARN) is a exoribonuclease responsible for the deadenylation of mRNA. This protein is constitutively expressed in virtually all mammalian tissues. With a critical role in the post-transcriptional control of gene expression PARN consists of two RNA-binding domains and one catalytic domain. Although PARN has a preference for poly(A), data suggests the protein can also degrade poly(U).
Catalog #130885
ApplicationsSuitable for use in Immunofluorescence and Western Blot. Other applications not tested.
Recommended DilutionImmunofluorescence: 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenFull length human PARN, aa1-639 (NP_002573.1).
SpecificityRecognizes human PARN. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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