Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Protein Kinases, Ribosomal » Anti -RPS6KB1 (STK14A, Ribosomal Protein S6 Kinase beta-1, 70kD Ribosomal Protein S6 Kinase 1, Ribosomal Protein S6 Kinase I, Serine/Threonine-protein Kinase 14A, p70 Ribosomal S6 Kinase alpha)

Anti -RPS6KB1 (STK14A, Ribosomal Protein S6 Kinase beta-1, 70kD Ribosomal Protein S6
Kinase 1, Ribosomal Protein S6 Kinase I, Serine/Threonine-protein Kinase 14A, p70
Ribosomal S6 Kinase alpha)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH IF
RPS6KB1 encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this rotein and overexpression of this kinase are seen in some breast cancer cell lines.
Catalog #132825
ApplicationsSuitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 10ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 0.5ug/ml
Optimal dilutions to be determined by the researcher.
AA SequencePSVLESVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSGIEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone No1E12
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPartial recombinant corresponding to aa416-526 from human RPS6KB1 (NP_003152) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human RPS6KB1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links