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You are here:Home » Antibodies » Abs to Chromogranin » Anti -SCG5 (Neuroendocrine Protein 7B2, Pituitary Polypeptide, SGNE1 Secretogranin V, Secretogranin-5, Secretory Granule Endocrine Protein I)

Anti -SCG5 (Neuroendocrine Protein 7B2, Pituitary Polypeptide, SGNE1 Secretogranin V,
Secretogranin-5, Secretory Granule Endocrine Protein I)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
SCG5 acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. It binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. It plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
Catalog #133001
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
AA SequenceEYPAHQAMNLVGPQSIEGGAHEGLQHLGPFGNIPNIVAELTGDNIPKDFSEDQGYPDPPNPCPVGKTDDGCLENTPDTAEFSREFQLHQHLFDPEHDYPGL*
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No8G11
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenPartial recombinant corresponding to aa59-160 from human SCG5 (NP_003011) with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human SCG5.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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