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You are here:Home » Antibodies » Abs to 14-3-3 » Anti -14-3-3

Anti -14-3-3

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Belongs to the 14-3-3 family. 14-3-3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14-3-3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis, including Raf, PKC, Bad, Cbl and c-Bcr. Interactions between 14-3-3 and target proteins are strongly influenced by the phosphorylation state of 14-3-3 and the target protein.
Catalog #135868
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Immunohistochemistry (Paraffin): 1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceRat
ConcentrationNot determined
FormSupplied as a liquid in HEPES (pH 7.5), 150mM NaCl, 100ug per ml BSA, 50% glycerol.
PurityPurified by immunoaffinity chromatography
ImmunogenSynthetic peptide corresponding to rat 14-3-3 at C-Terminal (KLH).
SpecificityRecognizes rat 14-3-3. Species Crossreactivity: Bovine, canine, chicken, human mouse, rat, xenopus.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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