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You are here:Home » Antibodies » Antibodies-Receptors » Anti -ADRA2A (Alpha-2A Adrenergic Receptor, Alpha-2A Adrenoreceptor, Alpha-2A Adrenoceptor, Alpha-2AAR, ADRA2R, ADRAR)

Anti -ADRA2A (Alpha-2A Adrenergic Receptor, Alpha-2A Adrenoreceptor, Alpha-2A
Adrenoceptor, Alpha-2AAR, ADRA2R, ADRAR)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH IF
The Alpha 2a- Adrenergic Receptor functions as a post-synaptic receptor that mediates the effects of epinephrine and norepinephrine. This adrenoceptor also functions as a presynaptic autoreceptor, inhibiting the subsequent release of neurotransmitter, especially epinephrine, from sympathetic nerves and from adrenergic neurons in the central nervous system. Adrenergic Alpha-2A Receptor polymorphisms have been identified in individuals with Tourette's syndrome. Furthermore, increased levels of plasma norepinephrine have been noted in children with attention-deficit hyperactivity disorder and learning disabilities. Mutant mice lacking both Alpha 2a and Alpha 2c Receptors exhibited increased plasma noradrenaline and developed cardiac hypertrophy by four months of age.
Catalog #135885
ApplicationsSuitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 1:100-1:500
ELISA: 1:20,000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography
ImmunogenSynthetic peptide corresponding to human ADRA2A at C-Terminal.
SpecificityRecognizes human ADA2A. Species Crossreactivity: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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