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You are here:Home » Antibodies » Abs to Enzymes, Phosphatase » Anti -CTDSP1 (Carboxy-terminal Domain RNA Polymerase II Polypeptide A Small Phosphatase 1, NLIIF, SCP1)

Anti -CTDSP1 (Carboxy-terminal Domain RNA Polymerase II Polypeptide A Small Phosphatase 1,
NLIIF, SCP1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E IH
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Catalog #136005
ApplicationsSuitable for use in ELISA, Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Immunohistochemistry (Paraffin): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-RGKGDQKSAASQK from human CTDSP1(NP_067021.1; NP_872580.1).
SpecificityRecognizes human CTDSP1. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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