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You are here:Home » Antibodies » Antibodies-Cullin » Anti -CUL1, CT (CUL1, Cullin 1)

Anti -CUL1, CT (CUL1, Cullin 1)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH IF
Cullin-1 is a negative regulator of the cell cycle that controls the abundance of G1 cyclins during embryogenesis; Cul1 mutants produce abnormally small cells due to an accelerated progression of the cell cycle G1-to-S-phases and the absence of mitotic arrest phase. Null mutations cause hyperplasia of all tissues. Cul-1 is part of the SCF ubiquitin ligase complex with S KP1 and F box-containing protein. Cul-1 is homologous to the yeast cdc53 protein.
Catalog #136008
ApplicationsSuitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 1:100-1:500
ELISA: 1:20,000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography
ImmunogenSynthetic peptide corresponding to human CUL1/Cullin 1 at C-Terminal.
SpecificityRecognizes human CUL1/Cullin 1. Species Crossreactivity: Mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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