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You are here:Home » Antibodies » Abs to Transcription Factors, STAT » Anti -PIAS4, CT (Protein Inhibitor of Activated STAT Protein 4, PIASy, PIASG)

Anti -PIAS4, CT (Protein Inhibitor of Activated STAT Protein 4, PIASy, PIASG)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
PAIS4/PAISY (Protein inhibitor of Stat 4) is a member of a family of proteins that inhibit activated STAT proteins and sown regulate the STAT-signaling pathway. Yeast 2 hybrid analysis showed that PIAS4 interacts with GATA2, a transcription factor involved in hematopoietic and cardiovascular development. Over expression of PIAS4 has been shown to cause either premature senescence or apoptosis, depending on cellular p53 and RB status.
Catalog #136331
ApplicationsSuitable for use in ELISA, Western Blot, Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:20,000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography
ImmunogenSynthetic peptide corresponding to human PIAS4 at C-Terminal.
SpecificityRecognizes human PIAS4. Species Crossreactivity: Mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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