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You are here:Home » Antibodies » Abs to Synuclein » Anti -SNCB, CT (SNCB, Beta-synuclein)

Anti -SNCB, CT (SNCB, Beta-synuclein)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH IF
The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease; however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene.
Catalog #136435
ApplicationsSuitable for use in Immunofluorescence, ELISA, Western Blot, Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 1:100-1:500
ELISA: 1:5000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography
ImmunogenSynthetic peptide corresponding to human SNCB/Beta-Synuclein at C-Terminal.
SpecificityRecognizes human SNCB/Beta-Synuclein. Species Crossreactivity: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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