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You are here:Home » Antibodies » Abs to Superoxide Dismutase » Anti -SOD3 (Extracellular Superoxide Dismutase [Cu-Zn], EC-SOD)

Anti -SOD3 (Extracellular Superoxide Dismutase [Cu-Zn], EC-SOD)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IP IH
This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminal before secretion to generate circulating tetramers that do not interact with the ECM. EC-SOD and iNOS mRNA and protein were expressed in smooth muscle cells and macrophages in early and advanced lesions (Luoma et al., 1998).
Catalog #136441
ApplicationsSuitable for use in ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:2000
Immunohistochemistry (Paraffin): 1:200
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,k
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol.
PurityPurified by ammonium sulfate precipitation.
ImmunogenRecombinant corresponding to human SOD3 expressed in E..coli.
SpecificityRecognizes human SOD3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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