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You are here:Home » Antibodies » Abs to Aquaporin » Anti -Aquaporin 1 (AQP1, CHIP29)

Anti -Aquaporin 1 (AQP1, CHIP29)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IF
Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquarporin 1 is a widely expressed water channel, found in the basolateral and apical plasma membranes of the proximal tubes, the descending loop of Henel and in the descending portion of the vasa recta. Additionally it is found in red blood cells, vascular endothelium, gastrointestinal tract, sweat glands and lungs. It is not regulated by vasopressin (3).
Catalog #136755
ApplicationsSuitable for use in Immunofluorescence and Western Blot. Other applications not tested.
Recommended DilutionImmunofluorescence: 1:200-400
Western Blot: 1:1000-4000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceRat
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide, 50% glycerol.
PurityAffinity Purified
ImmunogenSequence N-MASEFKKKLF (rat).
SpecificityRecognizes rat Aquaporin 1 at ~28.5kD. May detect larger glycosylated bands ~35-50kD. Species Crossreactivity: Human and mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAQP1, CHIP29


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