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You are here:Home » Biochemicals » Biochem-Antibiotics » BML-278, SIRT1 Inhibitor (N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine)

BML-278, SIRT1 Inhibitor (N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine)

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Specifications

A structurally novel activator of SIRT1 (EC150=1uM). Displays selectivity over SIRT2 and 3 (EC150=25 and 50uM respectively). Cell permeable.
Catalog #136761
SolubilityDMSO (~5mg/ml)
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular FormulaC24H25NO4
Molecular Weight391.5
SourceSynthetic
Purity~98% (TLC)
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS. Reconstitute with sterile dH20.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesN-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine


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