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You are here:Home » Antibodies » Antibodies-Synaptophysin » Anti -Synaptophysin (SYP, SYPH, Sypl, Syn p38)

Anti -Synaptophysin (SYP, SYPH, Sypl, Syn p38)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
Synaptophysin is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kD (1). It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for the presynaptic vesicle, and functions in synaptic vesicle exocytois, including cholesterol-dependent vesicle biogeneis, regulation of SNARE assembly via interaction with VAMP/synaptobrevin, formation of the fusion pore initiating neurotransmitter release, and activation of vesicle endocytosis (2, 3). This gene has also been implicated in X linked mental retardation (4).
Catalog #136851
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1.0ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone NoEP10
FormSupplied as a liquid in PBS, pH 7.4, 50% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenImmunoprecipitate of human brain.
SpecificityRecognizes human Native Synaptophysin at ~38kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSYP, SYPH, Sypl, Syn p38

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