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You are here:Home » Molecular Biology » MB-Proteins » AIDA, Recombinant, Human, aa1-306, His-Tag (Axin Interactor Dorsalization-associated, C1orf80, RP11-378J18.7)

AIDA, Recombinant, Human, aa1-306, His-Tag (Axin Interactor Dorsalization-associated,
C1orf80, RP11-378J18.7)

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Specifications

AIDA acts as a ventralizing factor during embryogenesis. This protein inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin- independent dorsalization pathway activated by AXIN/JNK-signaling.
Catalog #136993
SourceRecombinant protein corresponding to human AIDA, fused to His-tag at N-terminal expressed in E.coli.
Molecular Weight~37.4kD (329aa) (MALDI-TOF)
AA SequenceMGSSHHHHHH SSGLVPRGSH MGSMSEVTRS LLQRWGASFR RGADFDSWGQ LVEAIDEYQI LARHLQKEAQ AQHNNSEFTE EQKKTIGKIA TCLELRSAAL QSTQSQEEFK LEDLKKLEPI LKNILTYNKE FPFDVQPVPL RRILAPGEEE NLEFEEDEEE GGAGAGSPDS FPARVPGTLL PRLPSEPGMT LLTIRIEKIG LKDAGQCIDP YITVSVKDLN GIDLTPVQDT PVASRKEDTY VHFNVDIELQ KHVEKLTKGA AIFFEFKHYK PKKRFTSTKC FAFMEMDEIK PGPIVIELYK KPTDFKRKKL QLLTKKPLYL HLHQTLHKE
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~37.4kD
SourceE.coli
Purity~90% (SDS-PAGE)
Concentration~0.1mg/ml
FormSupplied as a liquid in 20mM Tris-HCl buffer, pH 8.0,10% glycerol, 0.2M NaCl,1mM DTT.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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