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137095 IL34, Recombinant, Human, aa21-242, His-Tag (Interleukin 34, C16orf77, MGC34647) CAS:

Specifications
References
Grade
Purified
Molecular Weight
29.6
EU Commodity Code
30021019
Shipping Temp
Blue Ice
Storage Temp
-20°C

IL34, also known as Interleukin 34, is a protein belonging to a group of cytokines called interleukins. This protein increases growth or survival of immune cells known as monocytes; it elicits its activity by binding the Colony stimulating factor 1 receptor. It also has a potential role in viral infection, the adaptive immune response and bone marrow cell proliferation.

Source
Recombinant protein corresponding to human IL34, fused to His-tag at N-terminal expressed in E.coli.
Molecular Weight
~29.6kD (260aa)
AA Sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMNE PLEMWPLTQN EECTVTGFLR DKLQYRSRLQ YMKHYFPINY KISVPYEGVF RIANVTRLQR AQVSERELRY LWVLVSLSAT ESVQDVLLEG HPSWKYLQEV QTLLLNVQQG LTDVEVSPKV ESVLSLLNAP GPNLKLVRPK ALLDNCFRVM ELLYCSCCKQ SSVLNWQDCE VPSPQSCSPE PSLQYAATQL YPPPPWSPSS PPHSTGSVRP VRAQGEGLLP
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source
Recombinant, E. coli
Purity
~85% (SDS-PAGE)
Concentration
~1mg/ml
Form
Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 10% glycerol, 0.4M urea.
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
References
1. Lin H. et al. (2008) Science. 320:807-811. 2. Wang Y. et al. (2012) Nat Immunol. 13:753-760.
USBio References
No references available
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