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You are here:Home » Antibodies » Abs to Mitochondrial Proteins » Anti -CBARA1 (MICU1, Mitochondrial)

Anti -CBARA1 (MICU1, Mitochondrial)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Purified B
CBARA1/MICU1 is a mitochondrial protein associated to the mitochondrial inner membrane that is comprised of two EF hand helix-loop-helix motifs. CBARA1/MICU1 is involved in mitochondrial calcium entry, metabolic coupling between cytosolic calcium transients, and activation of matrix dehydrogenases (1). Mitochondrial CBARA1/MICU1 is required to preserve normal mitochondrial calcium concentration below the equilibrium level by interacting with the uniporter pore-forming subunit MCU (2). CBARA1/MICU1 is important in pancreatic beta-cell mitochondrial calcium uptake and sustained insulin secretion (3).
Catalog #137423
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000. Incubate membrane with diluted antibody in 5% w/v BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No13G26
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied in 10mM sodium HEPES, pH 7.5, 150 mMNaCl, 100ug/ml BSA, 50% glycerol and <0.02% sodium azide.
PurityPurified.
ImmunogenSynthetic peptide corresponding to residues surrounding Lys110 of human CBARA1/MICU1.
SpecificityRecognizes endogenous levels of total human CBARA1/MICU1. Species Crossreactivity: mouse, rat, monkey.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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