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You are here:Home » Antibodies » Antibodies-PDZ Domain » Anti -GIPC (PDZ Domain-containing Protein GIPC2)

Anti -GIPC (PDZ Domain-containing Protein GIPC2)


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Clone Host Grade Applications
Monoclonal Mouse Purified E B
GIPC, GAIP interacting protein at the C-terminus, is a PDZ domain containing protein that interacts with RGS-GAIP. GIPC was also identified as TIP-2, a protein that interacts with the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating clathrin-coated vesicular trafficking. GIPC also associates with membrane bound semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain.
Catalog #138654
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
HybridomaMouse F0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No13L1
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
ImmunogenRecombinant protein corresponding to aa1-315 from human GIPC at C-terminal, expressed in E.coli.
SpecificityRecognizes human GIPC2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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