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You are here:Home » Molecular Biology » Growth Factors-TNF » LITAF, Recombinant, Human, aa1-161, His-Tag (Lipopolysaccharide-induced TNF-alpha Factor, PIG7, SIMPLE)

LITAF, Recombinant, Human, aa1-161, His-Tag (Lipopolysaccharide-induced TNF-alpha Factor,
PIG7, SIMPLE)

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Specifications

Lipopolysaccharide-induced TNF-alpha factor, also known as LITAF, is a small integral membrane protein of lysosome/late endosome. LITAF mediates the expression of inflammatory cytokines such as TNF-alpha in Lipopolysaccharide-induced processes. LITAF binds to STAT6B, a member of the STAT6 family forming a complex on the TNF-alpha promoter that modulates TNF activity. High levels of expression of LITAF mRNA have been observed predominantly in the placenta, peripheral blood leukocytes, lymph nodes and spleen.
Catalog #138689
SourceRecombinant protein corresponding to aa1-161 from human LITAF at N-terminal, fused to His-tag expressed in E.coli.
Molecular Weight~19.2kD (181aa)
AA SequenceMGSSHHHHHH SSGLVPRGSH MSVPGPYQAA TGPSSAPSAP PSYEETVAVN SYYPTPPAPM PGPTTGLVTG PDGKGMNPPS YYTQPAPIPN NNPITVQTVY VQHPITFLDR PIQMCCPSCN KMIVSQLSYN AGALTWLSCG SLCLLGCIAG CCFIPFCVDA LQDVDHYCPN CRALLGTYKR L
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~19.2kD
SourceE. coli
Purity~85% (SDS-PAGE)
Concentration~1mg/ml
FormSupplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.4M urea, 10% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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