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You are here:Home » Antibodies » Antibodies-Enzymes, Peroxidase » Anti -GPX-1 (Glutathione Peroxidase 1, Glutathione Peroxidase 1, GSHPx-1, Cellular Glutathione Peroxidase, GPX1)

Anti -GPX-1 (Glutathione Peroxidase 1, Glutathione Peroxidase 1, GSHPx-1, Cellular
Glutathione Peroxidase, GPX1)


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Clone Host Grade Applications
Polyclonal Rabbit Serum E B IH
Glutathione peroxidase 1 has a role in detoxification of hydrogen peroxide and is one of the most important antioxidant enzymes in humans. It exists as a homotetramer which localises to the cytoplasm. It belongs to the glutathione peroxidase family. Glutathione peroxidase 1 is one of few proteins in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. This protein has a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine repeats. The allele with five alanine repeats is significantly associated with breast cancer risk. At least two alternatively spliced isoforms have been identified.
Catalog #138835
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1000-1:4000
Western Blot: 1:1000-1:4000
Immunohistochemistry: 1:200-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
ConcentrationNot determined
FormSupplied as a lyophilized powder in 0.02% thimerosal. Reconstitute with sterile ddH2O.
ImmunogenSynthetic peptide corresponding to aa175-194, RRYSRRFQTIDIEPDIEALL, from human GPx-1, conjugated to diphtheria toxin.
SpecificityRecognizes human and rat cellular selenium dependent glutathione peroxidase.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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