Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Antibodies-Cadherin » Anti -CDH3 (Cadherin 3, Cadherin-3, Placental Cadherin, P-cadherin, CDHP)

Anti -CDH3 (Cadherin 3, Cadherin-3, Placental Cadherin, P-cadherin, CDHP)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH IC
CDH3 is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Its gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in its gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Catalog #139509
ApplicationsSuitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionELISA: 1:100-200
Western Blot: 1:100-400
Immunocytochemistry: 1:100-500 (formalin fixed cells)
Immunohistochemistry: 1:100-500 (formalin fixed frozen sections)
Immunohistochemistry: 1:50-200 (paraffin sections)
Optimal dilutions to be determined by the researcher.
AA SequenceMGHHHHHHSG SEF-GDDGDHFTIT THPESNQGIL TTRKGLDFEA KNQHTLYVEV TNEAPFVLKL PTSTATIVVH VEDVNEAPVF VPPSKVVEVQ EGIPTGEPVC VYTAEDPDKE NQKISYRILR DPAGWLAMDP DSGQVTAVGT LDREDEQFVR NNIYEVMVLA MDNGSPPTTG TGTLLLTLID VNDHGPVPEP RQITICNQSP VRQVLNITDK DLSPHTSPFQ AQLTDDSDIY WTAEVNEEGD TVVLSLKKFL KQDTYDVHLS LSDHGNKEQL TVIRATVCDC HGHVETCPGP WKGGFILPVL
Positive Control (Supplied)139509A: Supplied as a recombinant protein CDHP (Gly371~Leu660) in 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol, BPB 0.01%, NaN3 0.02%.
DAB: 10ul/well
ECL: 5ul/well
Store at -20°C. Stable for 6 months after receipt.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.02% sodium azide, 50% glycerol.
PurityPurified by affinity chromatography.
ImmunogenRecombinant protein corresponding to aa371-660 with N-terminal His-tag of human CDH3, expressed in E. coli
SpecificityRecognizes human CDH3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links