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You are here:Home » Growth Factors, Cytokines » Growth Factors-Exodus » CCL21, Recombinant, Mouse (Exodus-2, 6Ckine)

CCL21, Recombinant, Mouse (Exodus-2, 6Ckine)

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Specifications

Exodus-2, also known as CCL21 and 6Ckine, is a novel chemokine produced at high levels in human lymph node tissue and the spleen. 6Ckine signals through the CCR7 receptor to recruit thymocytes and activated T cells in vitro, but is not known to be chemotactic for monocytes. Human and mouse Exodus-2 share > 85% amino acid identity.
Catalog #142851
SourceRecombinant protein corresponding to 110aa from mouse Exodus-2 expressed in E.coli.
Molecular Weight~12kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by its ability to chemoattract 5-10 day old cultures of human peripheral blood lymphocytes at concentrations between 200ng/ml- 600ng/ml.
AA SequenceSDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~12kD
SourceE.coli
Purity~98% (SDS-PAGE)
FormSupplied as a lyophilized powder. No additives. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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