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You are here:Home » Molecular Biology » MB-Lectins » Galectin-3, Recombinant, Human (Galactose-specific Lectin-3, IgE-binding Protein, MAC2, L-29 CPB-35)

Galectin-3, Recombinant, Human (Galactose-specific Lectin-3, IgE-binding Protein, MAC2,
L-29 CPB-35)

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Specifications

Galectin-3 belongs to a large family of carbohydrate-binding proteins called lectins. Galectin-3 is expressed by a wide range of cell types including activated T cells, tumor cells, macrophages, osteoclasts, fibroblasts and epithelial cells and interacts with b-galactoside sugar moieties. Galectin-3 is associated with cancer, heart failure, stroke and inflammation. Human and mouse Galectin-3 share an 80% homology by amino acid sequence.
Catalog #142877
SourceRecombinant protein corresponding to human Galectin-3 expressed in E.coli.
Molecular Weight~26kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the ability to induce chemotaxis of human PBMCs at concentrations ranging 2-220ug/ml.
AA SequenceADNFSLHDAL SGSGNPNPQG WPGAWGNQPA GAGGYPGASY PGAYPGQAPP GAYPGQAPPG AYHGAPGAYP GAPAPGVYPG PPSGPGAYPS SGQPSAPGAY PATGPYGAPA GPLIVPYNLP LPGGVVPRML ITILGTVKPN ANRIALDFQR GNDVAFHFNP RFNENNRRVI VCNTKLDNNW GREERQSVFP FESGKPFKIQ VLVEPDHFKV AVNDAHLLQY NHRVKKLNEI SK
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~26kD
SourceE.coli
Purity~97% (Reducing and non-reducing)
FormSupplied as a lyophilized powder in 10mM Na2PO4, pH 7.5, 50mM sodium chloride. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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