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You are here:Home » Molecular Biology » MB-Adipocytes, Adipogenesis » Globular ACRP-30, Recombinant, Human (gACRP-30, Adiponectin, Apm-1, Adipolean)

Globular ACRP-30, Recombinant, Human (gACRP-30, Adiponectin, Apm-1, Adipolean)

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Specifications

Globular ACRP-30, gACRP-30, is a naturally occurring cleavage product of adiponectin, a molecule made exclusively by adipocytes. gACRP-30 is detected a relatively high concentrations in the serum and is thought to play an important role in hyperglycemia and insulin resistance. gACRP-30 signals through receptors, AdipoR1 and AdipoR2.
Catalog #142880
SourceRecombinant protein corresponding to 145aa from human gACRP-30 expressed in E.coli.
Molecular Weight~16.7kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the ability to inhibit the proliferation of mouse M1 cells and is typically 1.0-2.5ug/ml.
AA SequenceMKGEPGEGAY VYRSAFSVGL ETYVTIPNMP IRFTKIFYNQ QNHYDGSTGK FHCNIPGLYY FAYHITVYMK DVKVSLFKKD KAMLFTYDQY QENNVDQASG SVLLHLEVGD QVWLQVYGEG ERNGLYADND NDSTFTGFLL YHDTN
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~16.7kD
SourceE.coli
Purity~95% (Reducing and non-reducing SDS-PAGE)
FormSupplied as a lyophilized powder in 10mM Tris, pH 8.0, 0.75mM DTT. Reconstitute with sterile 5mM Tris, pH 8.0, 0.75mM DTT.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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