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You are here:Home » Molecular Biology » Growth Factors-GM-CSF » GM-CSF, Recombinant, Human, Animal Free (Granulocyte Macrophage Colony Stimulating Factor, AF, CSF-2. Pluripoietin-alpha, MGI1GM)

GM-CSF, Recombinant, Human, Animal Free (Granulocyte Macrophage Colony Stimulating Factor,
AF, CSF-2. Pluripoietin-alpha, MGI1GM)

Pricing

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Specifications

Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is hematopoietic factor produced by endothelial cells, monocytes, fibroblasts and T cells in response to a number of inflammatory mediators. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages. Human and mouse GM-CSF show no cross-reactivity.
Catalog #142883
SourceRecombinant protein corresponding to 128aa from human Granulocyte Macrophage Colony Stimulating Factor expressed in E.coli.
Molecular Weight~14.6kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the dose-dependent induction of human TF-1 cell proliferation and is typically <0.1ng/ml.
AA SequenceMAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~14.6kD
SourceE.coli
Purity~95% (Reducing and non-reducing SDS-PAGE)
FormSupplied as a lyophilized powder in 10mM Na2PO4, pH 7.5. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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