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You are here:Home » Molecular Biology » Growth Factors-GRO » GRO gamma, Recombinant, Human (Macrophage Inflammatory Protein-2 Beta, Gro-y, MIP-2beta, CXCL3, GRO3)

GRO gamma, Recombinant, Human (Macrophage Inflammatory Protein-2 Beta, Gro-y, MIP-2beta,
CXCL3, GRO3)

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Specifications

Growth Regulated Proteins (GRO) are a group of three proteins, GRO-a, -b and -y, that are encoded by three distinct genes. All 3 GRO proteins can bind to the same receptors, but with differing affinities, and stimulate a number of biological responses including chemotaxis, angiogenesis, and growth regulation. More specifically, GROy (also called CXCL3), can act through chemokine receptor CXCR2 to promote monocyte migration and adhesion.
Catalog #142885
SourceRecombinant protein corresponding to 73aa human GROy expressed in E.coli.
Molecular Weight~7.9kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the ability to chemoattract human neutrophils at concentrations between 10-100ng/ml.
AA SequenceASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~7.9kD
SourceE.coli
Purity~98% (Reducing and non-reducing SDS-PAGE, HPLC)
FormSupplied as a lyophilized powder in 10mM Na2PO4, pH 7.5. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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