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You are here:Home » Molecular Biology » MB-Hormones, Steroids » Growth Hormone, Recombinant, Human (Somatotropin)

Growth Hormone, Recombinant, Human (Somatotropin)

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Specifications

Growth Hormone (GH) is an important growth factor made in and secreted throughout the body by the anterior pituitary gland. It stimulates growth and cell reproduction and regeneration in humans and other animals. The inability to appropriately produce or respond to GH results in diseases of decreased stature in children and adults. Although GH is used to treat several growth disorders, it is thought to be a very complex hormone with many of its functions yet to be uncovered.
Catalog #142886
SourceRecombinant protein corresponding to 192aa from human GH expressed in E.coli.
Molecular Weight~22.2kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the ability to induce proliferation of PDF 9D11 cells for this effect and is typically 0.5-0.8ng/ml.
AA SequenceMFPTIPLSRL FDNAMLRAHR LHQLAFDTYQ EFEEAYIPKE QKYSFLQNPQ TSLCFSESIP TPSNREETQQ KSNLELLRIS LLLIQSWLEP VQFLRSVFAN SLVYGASDSN VYDLLKDLEE GIQTLMGRLE DGSPRTGQIF KQTYSKFDTN SHNDDALLKN YGLLYCFRKD MDKVETFLRI VQCRSVEGSC GF
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~22.2kD
SourceE.coli
Purity~98% (Reducing and non-reducing SDS-PAGE)
FormSupplied as a lyophilized powder in 20mM NaHCO3, pH 8.0. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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