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You are here:Home » Molecular Biology » Growth Factors-Interleukin » Interleukin 13, Recombinant, Mouse (IL-13, NC30)

Interleukin 13, Recombinant, Mouse (IL-13, NC30)

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Specifications

Interleukin-13 (IL-13) is an important cytokine secreted from Th2 cells. The functions attributed to IL-13 overlap significantly with those of IL-4 (induces IgE secretion from B cells and inhibits expression of inflammatory cytokines such as IL-1b, TNF-a, IL-8 and IL-6), but differs from IL-4 in that IL-13 seems to link inflammatory response of immune cells to the pathophysiological changes in the surrounding non-immune cells. The receptor subunits of IL-13 consist of IL-4Ra, IL-13Ea1 and IL-13Ra2. Human and mouse IL-13 are cross-reactive.
Catalog #142894
SourceRecombinant protein corresponding to 111aa from mouse IL-13 expressed in E.coli.
Molecular Weight~12.3kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the dose dependent proliferation of TF-1 cells and is typically <4ng/ml.
AA SequenceMPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~12.3kD
SourceE.coli
Purity~95% (Reducing and non-reducing SDS-PAGE).
FormSupplied as a lyophilized powder no additives. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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