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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » Interleukin 17F, Recombinant, Mouse (IL-17F, Interleukin-17F)

Interleukin 17F, Recombinant, Mouse (IL-17F, Interleukin-17F)

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Specifications

Interleukin 17F (IL-17F) is one of six members of the IL-17 family (IL-17A-F) secreted by activated CD4+ T cells and monocytes. Similar to IL-17A, IL-17F binds to the IL17 RC receptor and promotes the production of IL-6, IL-8, G-CSF and increases matrix turnover rates. IL-17F is also thought to inhibit angiogenesis and induce endothelial cells to produce IL-2, MCP-1 and TGF-b1.
Catalog #142915
SourceRecombinant protein corresponding to two 133aa chains mouse IL-17F expressed in E.coli.
Molecular Weight~30kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the dose-dependant induction of IL-6 in NIH 3T3 cells and is typically 35-50ng/ml.
AA SequenceMRKNPKAGVP ALQKAGNCPP LEDNTVRVDI RIFNQNQGIS VPREFQNRSS SPWDYNITRD PHRFPSEIAE AQCRHSGCIN AQGQEDSTMN SVAIQQEILV LRREPQGCSN SFRLEKMLLK VGCTCVKPIV HQAA
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~30kD
SourceE.coli
Purity~98% (HPLC, Reducing and non-reducing SDS-PAGE)
FormSupplied as a lyophilized powder. No additives. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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