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You are here:Home » Molecular Biology » Growth Factors-Interleukin » Interleukin 4, Recombinant, Mouse, Animal Free (IL-4, AF, B Cell Stimulating Factor, BSF-1, BCDF, BCGF)

Interleukin 4, Recombinant, Mouse, Animal Free (IL-4, AF, B Cell Stimulating Factor,
BSF-1, BCDF, BCGF)

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Specifications

Interleukin-4 (IL-4) is an immuno-modulatory cytokine, produced primarily by a subgroup of helper T cells, known as Th2. IL-4 is known to induce naïve helper T cells to differentiate to Th2 cells, which subsequently produce more IL-4. Th2 cells regulate a wide variety of other immune cells including, Bcells, where it has the ability to promote IgG to IgE isotype switching.
Catalog #142939
SourceRecombinant protein corresponding to 121aa from mouse IL-4 expressed in E.coli.
Molecular Weight~13.5kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by dose-dependent induction of HT-2 cell proliferation and is typically <2ng/ml.
AA SequenceMHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~13.5kD
SourceE.coli
Purity~95% (Reducing and non-reducing SDS-PAGE, HPLC)
FormSupplied as a lyophilized powder. No additives. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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