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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » Interleukin 5, Recombinant, Mouse (IL-5, EDF, BCDFII, TRF)

Interleukin 5, Recombinant, Mouse (IL-5, EDF, BCDFII, TRF)

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Specifications

Interleukin-5 (IL-5) is a hematopoietic growth factor expressed in Th2, mast cells and eosinophils. IL-5 acts through its receptor, the IL-5 receptor (IL-5R) and is involved in B cell growth and eosinophil activation. IL-5 has been shown to be and is regulated by GATA-3, in addition to other transcription factors. Human and mouse IL-5 are cross-reactive.
Catalog #142940
SourceRecombinant protein corresponding to two 113aa chains from mouse IL-5 expressed in
E.coli.
Molecular Weight~26.2kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the dose-dependent induction of TF-1 cell proliferation and is typically <2ng/ml.
AA SequenceMEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~26.2kD
SourceE.coli
Purity~97% (Reducing and non-reducing SDS-PAGE, HPLC)
FormSupplied as a lyophilized powder in 20mM Na2PO4, pH 7.5. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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