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You are here:Home » Molecular Biology » Growth Factors-MCP » MCP-1, Recombinant, Mouse (Monocyte Chemotactic Protein-1, CCL2, JE, MCAF)

MCP-1, Recombinant, Mouse (Monocyte Chemotactic Protein-1, CCL2, JE, MCAF)

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Specifications

Monocyte Chemotactic Protein 1 (MCP-1), also known as CCL2, is thought to be produced by injured or infected tissues. MCP-1 signals through G protein-coupled receptors, CCR2 and CCR4, to recruit memory T cells, monocytes and dendritic cells.
Catalog #142951
SourceRecombinant protein corresponding to 125aa from mouse MCP-1 expressed in E.coli.
Molecular Weight~13.8kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by its ability to chemoattract human PBMCs or THP-1 cells at 4-15ng/ml.
AA SequenceQPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN
Storage and Stability Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~13.8kD
SourceE.coli
Purity~98% (HPLC, Reducing and non-reducing SDS-PAGE)
FormSupplied as a lyophilized powder. No additives. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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