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You are here:Home » Growth Factors, Cytokines » Growth Factors-MCP » MCP2, Recombinant, Human (Monocyte Chemotactic Protein-2, MCP-2, CCL8, HC14)

MCP2, Recombinant, Human (Monocyte Chemotactic Protein-2, MCP-2, CCL8, HC14)

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Specifications

Monocyte Chemotactic Protein 2 (MCP-2), also known as CCL8, is implicated in allergic responses through its ability to activate mast cells, eosinophils, and basophils. MCP-2 is known to signal through several G protein-coupled receptors including, CCR1, CCR2B, and CCR5.
Catalog #142952
SourceRecombinant protein corresponding to 76aa from human MCP-2 expressed in E.coli.
Molecular Weight~8.9kD
Endotoxin 1EU/ug
Biological ActivityThe activity is determined by the ability to chemoattract human PBMCs and is typically in the range of 10-100ng/ml.
AA SequenceQPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~8.9kD
SourceE.coli
Purity~98% (HPLC, Reducing and non-reducing SDS-PAGE).
FormSupplied as a lyophilized powder. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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