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You are here:Home » Molecular Biology » MB-Neurotrophins » NT-4, Recombinant, Humaman (Neurotrophin-4, NT-4/5, Neurotrophin 5, NT-5, Neurotrophic Factor)

NT-4, Recombinant, Humaman (Neurotrophin-4, NT-4/5, Neurotrophin 5, NT-5, Neurotrophic
Factor)

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Specifications

Neurotrophin-4 (NT-4) is an important member of the nerve growth factor (NGF) family of proteins along with NT-3, BDNF and NGF. Neurotrophins act in a paracrine and/or autocine manner to control neuronal numbers and dendrite outgrowth. These functions are thought to be communicated by TrkB, a receptor tryrosine kinase that NT-4 shares with BDNF.
Catalog #142964
SourceRecombinant protein corresponding to two 131aa from human NT-4 expressed in E.coli.
Molecular Weight~28.1kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the dose-dependent proliferation of C6 cells and is typically in the range of 1-5ug/ml.
AA SequenceMGVSETAPAS RRGELAVCDA VSGWVTDRRT AVDLRGREVE VLGEVPAAGG SPLRQYFFET RCKADNAEEG GPGAGGGGCR GVDRRHWVSE CKAKQSYVRA LTADAQGRVG WRWIRIDTAC VCTLLSRTGR A
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE.coli
Purity~97% (HPLC, Reducing and non-reducing SDS-PAG)
FormSupplied as a lyophilized powder. No additives. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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