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You are here:Home » Growth Factors, Cytokines » Growth Factors-SDF » Stromal Cell-Derived Factor-1 beta, Recombinant, Human (SDF-1beta, CXCL12, PBSF)

Stromal Cell-Derived Factor-1 beta, Recombinant, Human (SDF-1beta, CXCL12, PBSF)

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Specifications

Stromal cell Derived Growth Factor-1 beta (SDF-1b), also called CXCL12, is one of two splice variants made by a wide variety of cells when stimulated by inflammatory cytokines such as, TNF, IL-1 or LPS. SDF-1b signals through the G protein-couple receptor, CXCR4, to recruit activated leukocytes. Human SDF-1b shares 100% identity to feline SDF-1b.
Catalog #142983
SourceRecombinant protein corresponding to 72aa from human SDF-1b expressed in E.coli.
Molecular Weight~8.5kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by its ability to chemoattract human T cells at 10-75ng/ml.
AA SequenceKPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRF KM
Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~8.5kD
SourceE.coli
Purity~97% (HPLC, Reducing and non-reducing SDS-PAGE)
FormSupplied as a lyophilized powder. No additives. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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