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You are here:Home » Molecular Biology » Growth Factors-TARC » TARC, Recombinant, Human (CCL17, TARC, CCL17, Thymus and Activation Regulated Chemokine, ABCD-2, SCYA17)

TARC, Recombinant, Human (CCL17, TARC, CCL17, Thymus and Activation Regulated Chemokine,
ABCD-2, SCYA17)

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Specifications

Thymus and activation regulated chemokine (TARC), also known as CCL17, is a chemokine produced by thymus tissue constitutively and activated PBMCs (mainly DCs). TARC signals through the CCR4 receptor to induce chemotaxis of Th2 cells. TARC is thought to be important in asthma and allergic diseases, along with bacterial and viral infections.
Catalog #142985
SourceRecombinant protein corresponding to 71aa from human TARC expressed in E.coli.
Molecular Weight:
~8.1kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the ability to chemoattract human T cells at 2-40ng/ml.
AA SequenceARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~8.1kD
SourceE.coli
Purity~98% (HPLC, Reducing and non-reducing SDS-PAGE).
FormSupplied as a lyophilized powder in 0.02% TFA. Reconstitute with sterile dH2O.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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