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You are here:Home » Molecular Biology » MB-Thrombopoietin » Thrombopoietin, Recombinant, Human (TPO, Megakaryocyte Colony Stimulating Factor, c-MPL Ligand, MGDFer)

Thrombopoietin, Recombinant, Human (TPO, Megakaryocyte Colony Stimulating Factor, c-MPL
Ligand, MGDFer)

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Specifications

Thrombopoietin (TPO) is a growth factor that is produced by liver and kidney tissue. TPO acts through the TPO receptor to promote megakaryocyte maturation and differentiation, which leads to the production of platelets.
Catalog #142986
SourceRecombinant protein corresponding to 174aa from human TPO expressed in E.coli.
Molecular Weight~18.6kD
Endotoxin Level 1EU/ug (LAL)
Biological ActivityThe activity is determined by the dose-dependent stimulation of MO7e cells and is typically less than 1ng/ml.
AA SequenceSPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QLPPQGRTTA HKDPNAIFLS FQHLLRGKVR FLMLVGGSTL CVRRAPPTTA VPSRTSLVLT LNEL
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~18.6kD
Purity~98% (Reducing and non-reducing SDS-PAGE)
FormSupplied as a lyophilized powder in 10mM Na2PO4, pH 8.0. Reconstitute with 5mM Na2PO4, pH 7.5.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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