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You are here:Home » Molecular Biology » MB-Thrombopoietin » Thrombopoietin, Recombinant, Mouse (TPO, Megakaryocyte Colony Stimulating Factor, c-MPL Ligand, MGDF)

Thrombopoietin, Recombinant, Mouse (TPO, Megakaryocyte Colony Stimulating Factor, c-MPL
Ligand, MGDF)

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Specifications

Thrombopoietin (TPO) is a growth factor that is produced by the liver and kidney. TPO acts through the TPO receptor to promote megakaryocytematurationanddifferentiation,whichleadstotheproductionofplatelets.
Catalog #142988
SourceRecombinant protein corresponding to 174aa from mouse TPO expressed in E.coli.
Molecular Weight~18.7kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the dose-dependent stimulation of MO7e cells and is typically <1ng/ml.
AA SequenceSPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~18.7kD
SourceE.coli
Purity~97% (Reducing and non-reducing SDS-PAGE)
FormSupplied as a lyophilized powder in 10mM Na2PO4, pH 7.5. Reconstitute with sterile H20.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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