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You are here:Home » Molecular Biology » Growth Factors-TGF » Transforming Growth Factor beta 3, Recombinant, Mouse (TGF-b3)

Transforming Growth Factor beta 3, Recombinant, Mouse (TGF-b3)

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Specifications

The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-b isoforms (TGF-b1, -b2 and -b3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-b3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-b3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis.
Catalog #142994
SourceRecombinant protein corresponding to two 112aa chains from mouse TGF-b3 expressed in E.coli.
Molecular Weight~25.5kD
Endotoxin 1EU/ug (LAL)
Biological ActivityThe activity is determined by the cell toxicity assay, using the WHO Standard 98/608 as a direct comparison, and is typically <0.05ng/ml.
AA SequenceALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight~25.5kD
SourceE.coli
Purity~98% (Reducing and non-reducing SDS-PAGE)
FormSupplied as a liquid in 20% ethanol, 0.12% acetic acid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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